"In recent updated meta-analyses of prospective cohort studies, almost all foods revealed statistically significant associations with mortality risk. Substantial deficiencies of key nutrients (e.g. vitamins), extreme over-consumption of food, and obesity from excessive calories may indeed increase mortality risk. However, can small intake differences of specific nutrients, foods, or diet patterns with similar calories causally, markedly, and almost ubiquitously affect survival?"
"Nutritional epidemiology is a scandal. It should just go to the waste bin."
- Dr. John Ioannidis, JAMA